A technologist is reviewing a blood smear of a patient.She notices 85% blasts present, but is having a difficult time identifying the lineage.Cytochemical staining is subsequently performed, and the results for MPO, SBB, and NSE come back negative.Based on this information, what is the most likely lineage of the unknown blasts?

Question

Quizplus · Accepted Answer

The negative results for MPO, SBB, and NSE suggest that the blasts are not of myeloid or monocytic lineage. As erythroid lineage typically presents with morphological characteristics and the absence of cytoplasmic granules, it is unlikely that the blasts in question are erythroid. Therefore, lymphoid lineage is the most likely option.

A Technologist Is Reviewing a Blood Smear of a Patient