Which analyte is the best indicator of the overall picture of the immune system in an HIV-positive patient?

Question

Quizplus · Accepted Answer

The absolute CD4 count is the best indicator of the overall picture of the immune system in an HIV-positive patient because CD4+ T cells are the main targets of the virus and their depletion is a hallmark feature of HIV disease progression. Monitoring CD4 counts allows clinicians to assess the degree of immunosuppression and determine the need for antiretroviral therapy and prophylaxis against opportunistic infections. While the relative lymphocyte count and WBC count can also provide useful information about the immune system, they are not as specific or sensitive as the CD4 count in the context of HIV infection.

Which Analyte Is the Best Indicator of the Overall Picture