-In a disease associated with a nucleotide repeat,anticipation is often noticed in subsequent generations,usually associated with a more severe phenotype.Which of the following is a more likely cause of anticipation?
A)There is more frequent unequal crossing over.
B)Subtle phenotypic nuances are more often sought by a physician.
C)Family members are exposed to the same mutagens.
D)Highly repeated sequences are expressed more often.
E)The sequences have greater stability in later generations.

Question

-In a disease associated with a nucleotide repeat,anticipation is often noticed in subsequent generations,usually associated with a more severe phenotype.Which of the following is a more likely cause of anticipation?
A)There is more frequent unequal crossing over. 
B)Subtle phenotypic nuances are more often sought by a physician. 
C)Family members are exposed to the same mutagens. 
D)Highly repeated sequences are expressed more often. 
E)The sequences have greater stability in later generations.

Quizplus · Accepted Answer

There is more frequent unequal crossing over.

-In a Disease Associated with a Nucleotide Repeat,anticipation Is Often