Which of the following sequences BEST summarizes the gradual development of atherosclerosis?
A) excess dietary cholesterol, plaque accumulation, blood vessel inflammation, blood glucose increase, immune response, cardiac shock
B) plaque ruptures blood vessels, immune response, inflammation, cholesterol accumulation, vessels narrow and harden, plaque repairs damage
C) blood vessel inflammation, restricted blood flow causes heart attack that damages coronary arteries, tissue damage ensues, immune response, lipids accumulate, plaque forms
D) artery lining is injured, inflammation, blood lipids seep beneath lining, immune cells engulf the lipids and become foam cells, fatty streaks form, plaque accumulates, blood flow is diminished to tissues "downstream" of area

Question

Quizplus · Accepted Answer

The sequence described in option D, beginning with artery lining injury and progressing through inflammation, lipid accumulation, foam cell formation, fatty streak formation, plaque accumulation and diminished blood flow, represents the gradual development of atherosclerosis. It is the most accurate and comprehensive summary of the process. The other options either do not include all of the necessary steps or include additional factors that are not as directly related to atherosclerosis.

Which of the Following Sequences BEST Summarizes the Gradual Development