Which of the following can be used to express a second transgene from a single mRNA?

Question

Quizplus · Accepted Answer

IRES (Internal Ribosome Entry Site) is a sequence that allows translation initiation in the middle of an mRNA sequence, independent of the 5' cap. This allows for expression of a second transgene from a single mRNA. Downstream AUG and alternative mRNA splicing signals do not necessarily provide this capability, and RNA editing sequences alter the sequence of an mRNA, rather than affecting its translation. Therefore, the correct choice is B (IRES).

Which of the Following Can Be Used to Express a Second