Which of the following is a major disadvantage of using a vector based on adeno-associated virus (AAV)rather than an adenovirus or a retrovirus?

Question

Quizplus · Accepted Answer

One major disadvantage of using AAV is its limited capacity to carry genetic material. AAV can only tolerate an insert of up to 4.5kb, which can be a disadvantage when larger genes or regulatory elements need to be delivered to cells. Adenovirus and retrovirus, on the other hand, can accommodate larger inserts of up to 36 kb and 8 kb, respectively. The other options listed (A-D) are not considered major disadvantages of using AAV vectors.

Which of the Following Is a Major Disadvantage of Using