The human genome encodes transcription factors that contain an acidic activation domain that is phosphorylated in response to increased levels of the second messenger cAMP.Which one of the following contains one of these activation domains?
A)CBP
B)CDK9
C)CREB
D)CTD

Question

Quizplus · Accepted Answer

The statement mentions that transcription factors with an acidic activation domain that is phosphorylated in response to cAMP are present in the human genome. Among the options given, only CREB (cAMP response element binding protein) contains one of these activation domains. CBP (CREB-binding protein) interacts with CREB, but does not have the activation domain. CDK9 (cyclin-dependent kinase 9) is a protein kinase that regulates transcription elongation but does not have the activation domain. CTD (C-terminal domain) refers to a domain in RNA polymerase II, which is involved in transcript elongation but does not contain the activation domain described in the question.

The Human Genome Encodes Transcription Factors That Contain an Acidic