Which of the following is the correct order of binding of general transcription factors to initiate transcription at RNA polymerase II promoters?
A)TFIID,TFIIB,Pol II,TFIIH
B)PolII,TFIID,TFIIB,TFIIH
C)TFIIB,PolII,TFIIH,TFIID
D)TFIID,TFIIH,TFIIB,PolII

Question

Quizplus · Accepted Answer

TFIID binds first to the TATA box within the promoter region, followed by TFIIB, which helps in recruiting Pol II along with TFIIF. TFIIH, with its helicase activity, is one of the last to bind, unwinding DNA at the transcription start site, thus initiating transcription.

Which of the Following Is the Correct Order of Binding