Current vectors used for gene therapy insert into the genome as a random event.All of the following are potential problems that may result from this method of integration except
A)activation of a proto-oncogene.
B)inactivation of a tumor-suppressor gene.
C)insertion in the middle of an essential gene.
D)expression of the transgenic gene.

Question

Quizplus · Accepted Answer

Expression of the transgenic gene is the intended outcome of gene therapy, and therefore not a problem that may result from random integration. The other choices are potential problems that may result from random integration, as activation of a proto-oncogene, inactivation of a tumor-suppressor gene, or insertion in the middle of an essential gene can all lead to altered or disrupted cell function and possibly cancerous growth.

Current Vectors Used for Gene Therapy Insert into the Genome