Imprinting affects the phenotype when

Question

Quizplus · Accepted Answer

When one allele is imprinted and the other is inactivated or deleted, the phenotype is affected because only one allele is functional. Imprinting refers to the differential expression of alleles based on their parental origin. In some cases, one allele is silenced or inactivated, leading to monoallelic expression of the gene. If the other allele is also inactivated or deleted, then there is no functional copy of the gene, resulting in a phenotype that may be different from the normal or wildtype phenotype. The other choices are incorrect because both alleles need to be affected or there needs to be an abnormal number of chromosomes for imprinting to affect the phenotype.

Imprinting Affects the Phenotype When