A male baby who has suffered from persistent Candida fungal infections and several bouts of pneumonia before the age of 6 months is found to have some developmental problems as well as low-set ears.Laboratory testing reveals an absence of T cells.What is the most likely diagnosis?

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Quizplus · Accepted Answer

The absence of T cells suggests a T cell deficiency, which is characteristic of DiGeorge syndrome. The recurrent fungal infections and pneumonia may also be indicative of a compromised immune system. The developmental problems and low-set ears are also common features of DiGeorge syndrome. Selective IgA deficiency and common variable immunodeficiency may present with recurrent infections, but they typically do not have an absence of T cells. Waldenström macroglobulinemia is a neoplasm of B cells and would not present with a T cell deficiency.

A Male Baby Who Has Suffered from Persistent Candida Fungal