A nitroblue tetrazolium test shows little color in cells observed under a microscope.What disease does this finding correlate with?

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Quizplus · Accepted Answer

A nitroblue tetrazolium test evaluates the ability of white blood cells to produce hydrogen peroxide, which is used to kill certain types of bacteria. Little to no color change in cells observed under a microscope indicates a deficiency in this ability, which is seen in patients with chronic granulomatous disease. This is due to a defect in the ability of the white blood cells to create reactive oxygen species, which are needed for bacteria to be killed.

A Nitroblue Tetrazolium Test Shows Little Color in Cells Observed