A Practicing Physician at a University Student Healthcare Facility Often

A practicing physician at a university student healthcare facility often recommends to student patients that they take large doses of vitamin C (ascorbic acid) to fend off colds during the semester.As director of the chemistry laboratory that serves this facility,you notice a trend in that many of this physician's students' serum creatinine levels are unusually high.You are currently using a type of analysis based on the Jaffe reaction.What might be the cause of the elevated values?

A) High doses of ascorbic acid cause increased hepatic synthesis of bilirubin,which interferes with the enzymes used in the assay.
B) Elevated ascorbic acid in serum produces a Jaffe-like chromogen in this analysis that can be interpreted as increased serum creatinine.
C) It may be that this physician's patients all are exhibiting increased muscle breakdown.
D) The ketones and ketoacids produced from the breakdown of creatinine in the students' serum are interfering with the development of the color reaction.