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Why Does Persistently Acidic Urine Lead to Formation of Uric

Question 9

Multiple Choice

Why does persistently acidic urine lead to formation of uric acid renal stones?


A) Uric acid has a pKa of 5.57,which makes it insoluble in acidic solutions.
B) At a pH of 10,uric acid is insoluble and aggregates to form stones.
C) Elevated urine purines cause uric acid crystals to aggregate and form stones.
D) Supersaturation of acidic urine causes calcium to form complexes with uric acid,which is the initial step in stone formation.

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