The metabolizing enzyme that catalyzes the transfer of an acetyl moiety from acetyl-CoA to homocyclic and heterocyclic arylamines and hydrazines in,for example,substrates related to cigarette smoke is:

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NAT1 (N-acetyltransferase 1) is the metabolizing enzyme that catalyzes the transfer of an acetyl moiety from acetyl-CoA to homocyclic and heterocyclic arylamines and hydrazines in substrates related to cigarette smoke. It is primarily expressed in the liver and has implications in drug metabolism and carcinogenesis. CYP2C6, CYP2D9, and UGT1A1 are not known to play a significant role in the metabolism of these substrates.

The Metabolizing Enzyme That Catalyzes the Transfer of an Acetyl