The HLA gene and its variants that have been associated most closely with drug hypersensitivity and that can be assessed in a laboratory is HLA-:

Question

Quizplus · Accepted Answer

The HLA-B gene and its variants are most closely associated with drug hypersensitivity reactions and can be assessed in a laboratory through genetic testing. HLA-A and HLA-C genes are also involved in immune responses to drugs, but their association with hypersensitivity reactions is not as strong as that of HLA-B. HLA-D is related to antigen presentation and is not directly involved in drug hypersensitivity reactions.

The HLA Gene and Its Variants That Have Been Associated