The classic experiment demonstrating that reduced and denatured RNase A could refold into the native form demonstrates that _______.
A)1° structure can determine 3° structure
B)denaturation does not disrupt protein 2° structure
C)disulfide bonds do not stabilize folded proteins
D)All of the above.
E)None of the above

Question

Quizplus · Accepted Answer

The experiment with RNase A shows that the primary structure (amino acid sequence) is sufficient to determine the final three-dimensional structure of the protein, indicating that choice A is correct. The experiment does not directly address the stability of protein secondary structure or the role of disulfide bonds in protein folding, so choices B and C are not supported.

The Classic Experiment Demonstrating That Reduced and Denatured RNase a Could