Which of the following occurs first when folding a disordered polypeptide chain into a stable protein formation?
A)formation of a low energy state
B)association of ordered subunits
C)aggregation of hydrophobic regions in the protein
D)tertiary structure refinement
E)formation of a low entropy state

Question

Quizplus · Accepted Answer

Aggregation of hydrophobic regions in a protein is a critical early step in protein folding, as these regions tend to avoid water and come together, helping to drive the folding process.

Which of the Following Occurs First When Folding a Disordered