Which statement is true regarding the activation of pyruvate carboxylase by acetyl-CoA?
A)Feedback activation enhances flux through glycolysis.
B)Feedforward activation enhances the entry of pyruvate through the TCA cycle as Acetyl-CoA.
C)Ensures that gluconeogenesis occurs rather than pyruvate conversion to acetyl-CoA.
D)Ensures that ATP is not wasted in the production of oxaloacetate.
E)Feedback inhibition ensures that excess glucose-6-phosphate is not produced.

Question

Quizplus · Accepted Answer

Acetyl-CoA activates pyruvate carboxylase to convert pyruvate to oxaloacetate, promoting gluconeogenesis when energy levels are high, rather than converting pyruvate to acetyl-CoA for the TCA cycle.

Which Statement Is True Regarding the Activation of Pyruvate Carboxylase