Which of the following best describes the role of fructose-2,6-bisphosphate (FBP)in liver cells?
A)It is an intermediate in glycolysis.
B)It is an intermediate in gluconeogenesis.
C)It is an intermediate in both glycolysis and gluconeogenesis.
D)FBP is a potent allosteric activator of phosphofructokinase and an inhibitor of fructose bisphosphatase.
E)FBP is a potent allosteric activator of fructose bisphosphatase and an inhibitor of phosphofructokinase.

Question

Quizplus · Accepted Answer

Fructose-2,6-bisphosphate (FBP) is not an intermediate in glycolysis or gluconeogenesis but acts as a potent allosteric activator of phosphofructokinase, which is a key enzyme in glycolysis, and as an inhibitor of fructose bisphosphatase, which is a key enzyme in gluconeogenesis. This regulatory role helps balance the rates of glycolysis and gluconeogenesis in liver cells.

Which of the Following Best Describes the Role of Fructose-2,6-Bisphosphate