Of the four molecules listed below,three of them reciprocally regulate phosphofructokinase 1 (PFK1)and fructose-1,6-bisphosphatase.Which molecule does NOT fit?

Question

Quizplus · Accepted Answer

Pyruvate is not a reciprocal regulator of PFK1 and fructose-1,6-bisphosphatase. However, the other three molecules listed (fructose-2,6-bisphosphate, citrate, and AMP) are all reciprocal regulators of PFK1 and fructose-1,6-bisphosphatase. Fructose-2,6-bisphosphate activates PFK1 and inhibits fructose-1,6-bisphosphatase, while citrate inhibits PFK1 and activates fructose-1,6-bisphosphatase. AMP activates PFK1 and inhibits fructose-1,6-bisphosphatase.

Of the Four Molecules Listed Below,three of Them Reciprocally Regulate