Lack of the complement inhibitor C1INH results in which disease?

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Hereditary angioedema is a disease characterized by recurrent episodes of subcutaneous or submucosal edema that can cause abdominal pain, laryngeal edema, and potentially life-threatening airway obstruction. It is caused by a deficiency or dysfunction of C1 inhibitor (C1INH), a complement inhibitor that regulates the activation of complement pathway, leading to excessive activation of the complement system and subsequent release of vasoactive peptides that cause edema.

Lack of the Complement Inhibitor C1INH Results in Which Disease