Which of the Following Is/are Clinical Application(s) of RT-PCR

Which of the following is/are clinical application(s) of RT-PCR?

A) Determine expression of selected genes by targeting their corresponding RNA transcripts
B) Detect certain disease-specific chromosomal translocations where RNA is transcribed across the translocation breakpoint
C) Detect minimal residual disease in cancer patients following therapy by amplifying tumor-specific fusion transcripts
D) Detect foreign organisms using probes targeting abundantly transcribed sequences or targeting viruses having RNA genomes
E) All of the above