If you wanted to permanently block the function of an enzyme, you could add

Question

Quizplus · Accepted Answer

Adding a molecule that covalently binds to the active site of the enzyme would permanently block the function of the enzyme by altering the shape of the active site and preventing the enzyme from binding to its substrate. Noncompetitive and allosteric inhibitors can be reversible and are not permanent solutions, while adding more product or competitive inhibitors would not permanently block the function of the enzyme.

If You Wanted to Permanently Block the Function of an Enzyme