Which statement about antisense RNA and RNAi is true?
A) Antisense RNA and RNAi both block translation, but antisense RNA is generally preferred.
B) Antisense RNA and RNAi both block translation, but RNAi is generally preferred.
C) Antisense RNA and RNAi both block transcription, but antisense RNA is generally preferred.
D) Antisense RNA and RNAi both block transcription, but RNAi is generally preferred.
E) Antisense RNA and RNAi are different names for the same technique.

Question

Quizplus · Accepted Answer

Antisense RNA and RNAi both involve the use of complementary RNA strands to either block translation or degradation of mRNA. However, RNAi is generally a more effective and specific method compared to antisense RNA, as it can target specific mRNA sequences with high specificity and can also induce degradation of multiple target mRNAs through the RNA-induced silencing complex (RISC). Therefore, B is the correct answer as RNAi is generally preferred over antisense RNA.

Which Statement About Antisense RNA and RNAi Is True