The ability of THC to produce a "high" seems to be related to
A) activation of the CB1 receptor.
B) inhibition of dopamine within the nucleus accumbens.
C) inactivation of GABA neurons in the cortex.
D) inactivation of the CB1 receptor.
E) release of cortisol from the adrenal glands.

Question

Quizplus · Accepted Answer

THC activates the CB1 receptor, which is primarily found in the brain, leading to the psychotropic effects associated with marijuana use.

Answer: B is incorrect because dopamine release is actually increased in the nucleus accumbens by THC.

Answer: C is incorrect because inactivation of GABA neurons in the cortex by THC would actually exacerbate the effects of other excitatory neurotransmitters and lead to seizures rather than a euphoric high.

Answer: D is incorrect because inactivation of the CB1 receptor would actually decrease the effects of THC, rather than prolonging or intensifying them.

Answer: E is incorrect because cortisol is a stress hormone and has no known association with the effects of THC.

The Ability of THC to Produce a "High" Seems to Be