The key factor in determining passage across the blood-brain barrier is __________.

Question

Quizplus · Accepted Answer

The key factor in determining passage across the blood-brain barrier is fat solubility. Molecules that are more fat-soluble are able to cross the barrier more easily and reach the brain. This is because the blood-brain barrier is composed of tightly packed cells that restrict the passage of most substances, allowing only fat-soluble molecules or those that have a specific transport mechanism to pass through. The other choices, such as protein linkages, stability in the brain, or spinal cord compatibility, are not as relevant for determining passage across the blood-brain barrier.

The Key Factor in Determining Passage Across the Blood-Brain Barrier