All are true for the enzyme-transition state complex EXCEPT:
A) It is designated as EX .
B) The enzyme stabilizes the transition-state complex more than it stabilizes the substrate complex.
C) The enzyme is "designed" to bind the transition-state structure more tightly than the substrate or product.
D) The energy barrier between ES and EX is less than the energy barrier between S and X
.
E) All are true.
Correct Answer:
Verified
Q1: In the hydrolysis of p-nitrophenylacetate by chymotrypsin
Q2: In the catalytic triad common to many
Q3: All are true for low-barrier hydrogen bonds
Q5: Most covalent catalysis is carried out by
Q6: The initial bond formation in the covalent
Q7: Because the pKa is near 7, _
Q8: Which of the following statements regarding enzymes
Q9: Metal ion catalysis include all EXCEPT:
A) increased
Q10: The transition state has an estimated life-time
Q11: The good transition state analog is one
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