Which of the following statement about eukaryotic DNA replication is INCORRECT?
A) Only one DNA polymerase is required to propagate a replication fork.
B) The same polymerase in humans is involved in proofreading and primer removal as well as lagging strand elongation.
C) The main DNA polymerase that elongates the leading strand has an intrinsic processivity factor.
D) Eukaryotes require two enzymes to remove RNA primers.
E) Chromatin must be dismantled in advance of replication forks and reassembled on daughter strands after the fork has passed through.

Question

Quizplus · Accepted Answer

Multiple DNA polymerases are required to properly replicate a eukaryotic genome, including different polymerases for leading and lagging strand synthesis as well as for proofreading and primer removal. Additionally, several accessory proteins are required for efficient replication fork progression. Thus, statement A) is incorrect.

Which of the Following Statement About Eukaryotic DNA Replication Is