Multiple mechanisms provide a series of checkpoints that function to maintain immunological self-tolerance. A breakdown in any one of these mechanisms is likely to lead to autoimmunity.
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Q4: Based on these data, Fc
Q5: Immune privileged sites, such as the
Q6: While relatively rare, individuals with a homozygous
Q7: Based on these data, Fc
Q8: During inflammation, some proteins undergo modification,
Q10: AIRE is a transcriptional regulator that promotes
Q11: All autoreactive CD4 T cells are not
Q12: Rheumatoid arthritis is often classified as
Q13: Nearly 80% of patients with autoimmune
Q14: Treg cells that express FoxP3 are
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