Nearly 80% of patients with autoimmune diabetes, also known as type 1 diabetes, have antibodies to the glutamic acid decarboxylase protein (GAD65) that is made by pancreatic $\beta$-islet cells. Yet, the role of autoantibodies directed at GAD65 in the initiation of this disease is currently unclear. How might autoantibodies to GAD65 arise if they are not involved in the onset or initiation of type 1 diabetes?

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The Answer of Nearly 80% of patients with autoimmune diabetes, also known as type 1 diabetes, have antibodies to the glutamic acid decarboxylase protein (GAD65) that is made by pancreatic $\beta$-islet cells. Yet, the role of autoantibodies directed at GAD65 in the initiation of this disease is currently unclear. How might autoantibodies to GAD65 arise if they are not involved in the onset or initiation of type 1 diabetes?

Nearly 80% of Patients with Autoimmune Diabetes, Also Known as Type