In addition to Peyer's patches that resemble systemic lymph nodes, the intestinal epithelium also contains several thousand isolated lymphoid follicles. Unlike the organized secondary lymphoid tissues in the mucosal immune system, these lymphoid follicles:
A) Contain mostly T cells and very few B cells
B) Develop only after birth in response to colonization by commensal microbes
C) Are not connected to the lymphatic system that drains to lymph nodes
D) Have no M cells to deliver gut antigens to the lymphocytes in the follicles
E) Are found only in the intestinal epithelium, and not in other mucosal epithelia

Question

Quizplus · Accepted Answer

Isolated lymphoid follicles develop after birth in response to colonization by commensal microbes, which is a key aspect of the development of the mucosal immune system.

In Addition to Peyer's Patches That Resemble Systemic Lymph Nodes