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Secretory IgA Produced in the Epithelium of Mucosal Surfaces Has

Question 20

Multiple Choice

Secretory IgA produced in the epithelium of mucosal surfaces has several functions in protective immunity. Among these are neutralization of pathogens or toxins in the gastrointestinal tract lumen or in epithelial cell endosomes, neutralization of pathogens or toxins that cross the epithelial barrier, and transport of pathogens or toxins across M cells for delivery to lamina propria dendritic cells. All of these functions share the common feature that they:


A) Fail to induce local inflammation in the gastrointestinal epithelium
B) Are efficient at inducing opsonization of pathogens for uptake by phagocytes
C) Are efficient at inducing complement activation
D) Fail to completely protect the epithelium from cytotoxic effects of pathogens
E) Induce IgA-secreting plasma cells to produce increased amounts of secretory IgA

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