Infection of mice with the bacterial pathogen, Citrobacter rodentium, elicits a protective immune response in the gastrointestinal tract. This protective response is characterized by two sequential waves of IL-22 production, both induced by IL-23. The early wave of IL-22 production (<day 8 post-infection) is likely produced by:
A) Lamina propria dendritic cells responding to PAMPs of the bacterial pathogen
B) Lamina propria macrophages responding to PAMPs of the bacterial pathogen
C) Naive CD4 T cells induced to differentiate into TH17 cells in the mesenteric lymph node
D) Lamina propria ILC3 cells stimulated by dendritic cell-produced IL-23
E) IgA immune complexes transporting bacterial antigens and stimulating lamina propria dendritic cells to produce IL-22
Correct Answer:
Verified
Q1: NOD proteins are intracellular sensors of infections
Q2: Salmonella typhimurium is the causative agent of
Q3: Purified CD4 T cells were stimulated
Q4: Analysis of human milk from lactating mothers
Q5: Mice lacking the poly Ig receptor (pIgR)
Q7: Oral inoculation with rotavirus, an intestinal pathogen,
Q8: The TACI receptor on B cells, which
Q9: Patients receiving hematopoietic stem cell transplants
Q10: The mucosal immune system provides protection for
Q11: Vibrio cholerae causes an acute diarrheal illness
Unlock this Answer For Free Now!
View this answer and more for free by performing one of the following actions
Scan the QR code to install the App and get 2 free unlocks
Unlock quizzes for free by uploading documents