Most effector T cells migrate out of secondary lymphoid organs and into tissues to exert their function. In which of the cases shown in Figure will the TH1 effector cell undergo long-lived interactions with its target cell, an infected macrophage? Assume all of the target cells shown below are infected with the pathogen recognized by the specific TH1 cells.
A)
B)
C)
D)
E)
An immunological synapse forms between effector T cells and their targets to regulate signaling and to direct the release of effector molecules
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