Some specialized subsets of $\alpha$:$\beta$ T cells complete their development in the thymus and avoid negative selection, in spite of having T-cell receptors with high affinity for self-MHC complexes.

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Quizplus · Accepted Answer

This statement is true. Some specialized subsets of F1F1F1S1F1F1F10:F1F1F1S1F1F1F10 T cells, such as regulatory T cells, complete their development in the thymus and can avoid negative selection, even though they have T-cell receptors with high affinity for self-MHC complexes.

Some Specialized Subsets Of α\alphaα β\betaβ T Cells Complete Their Development in the Thymus and Avoid

Some Specialized Subsets Of $\alpha$ $\beta$ T Cells Complete Their Development in the Thymus and Avoid