Even when the complement cascade fails to proceed beyond generating the C3 convertase, complement activation is effective at inducing pathogen uptake and destruction. This process of immune protection is mediated by:
A) Activation of complement inhibitory receptors on phagocytes that promote pathogen uptake
B) Activation of soluble proteases in the serum that disrupt pathogen membranes
C) Engagement of complement receptors on phagocytes by C3b and its cleavage products which promotes phagocytosis
D) Engagement of complement receptors on B cells that promotes antibody production
E) Stimulation of antimicrobial peptide secretion by phagocytes

Question

Quizplus · Accepted Answer

When the complement cascade generates the C3 convertase, it leads to the production of C3b and its cleavage products. These products can engage complement receptors on phagocytes, which promote phagocytosis and therefore pathogen uptake and destruction.

Even When the Complement Cascade Fails to Proceed Beyond Generating