Given are five KM values for the binding of substrates to a particular enzyme. Which has the strongest affinity when k−1 is greater than k2?
A) 150 mM
B) 0.15 mM
C) 150 M
D) 1.5 nM
E) 15,000 pM

Question

Quizplus · Accepted Answer

In the given condition, when k−1 > k2, the lower the KM value, the stronger the affinity of the enzyme towards the substrate. Among the given options, 1.5 nM (D) has the lowest KM value, indicating the strongest affinity of the enzyme towards the substrate.

Given Are Five KM Values for the Binding of Substrates