Question 1

Instructions: Draw the structure of the aldol self-condensation product of each compound for the following question(s). If a compound does not undergo aldol self-condensation, explain why it does not.
Draw and explain:

Accepted Answer

The answer of Instructions: Draw the structure of the aldol...

Question 2

Instructions: Each of the following compounds in the following question(s) can be prepared by a mixed aldol condensation reaction.
 a)	Give the structures of the aldehyde and/or ketone precursors for each aldol condensation product and formulate the reaction.
b)	Give the structure of the intermediate aldol product.

Refer to instructions. Use the following compound:

Accepted Answer

a)

b)

Question 3

Instructions: Consider the reaction below to answer the following question(s).
 Refer to instructions. Draw the structure of the enolate ion that is generated during the course of this reaction.

Accepted Answer

The answer of Instructions: Consider the reaction below to answer...

Question 4

Instructions: Consider the structures below to answer the following question(s).  Refer to instructions. Underline the acidic hydrogen atoms in each of the molecules.

Accepted Answer

The answer of Instructions: Consider the structures below to answer...

Question 5

Instructions: Each of the following compounds in the following question(s) can be prepared by a mixed aldol condensation reaction.
 a)	Give the structures of the aldehyde and/or ketone precursors for each aldol condensation product and formulate the reaction.
b)	Give the structure of the intermediate aldol product.

Refer to instructions. Use the following compound:

Accepted Answer

The answer of Instructions: Each of the following compounds in...

Question 6

Which of the following does not possess an enol form? Explain your choice.

Accepted Answer

The answer of Which of the following does not possess...

Question 7

Instructions: Consider the reaction below to answer the following question(s).
 Refer to instructions. This reaction is an example of:

Accepted Answer

The answer of Instructions: Consider the reaction below to answer...

Question 8

Instructions: Draw the structure of the aldol self-condensation product of each compound for the following question(s). If a compound does not undergo aldol self-condensation, explain why it does not.
Draw and explain:

Accepted Answer

The answer of Instructions: Draw the structure of the aldol...

Question 9

Predict the major aldol product of the following reaction.

Accepted Answer

The answer of Predict the major aldol product of the...

Question 10

Instructions: Consider the reaction below to answer the following question(s).
 Refer to instructions. The product of this reaction is:

Accepted Answer

The answer of Instructions: Consider the reaction below to answer...

Question 11

Rank the following hydrogens in terms of decreasing acidity (most acidic > least acidic):

Accepted Answer

The answer of Rank the following hydrogens in terms of...

Question 12

Instructions: Draw the structure of the product you would expect to obtain by Claisen condensation of the esters shown in the question(s) below. If an ester does not undergo Claisen condensation, explain why it does not.
Draw and explain:

Accepted Answer

The answer of Instructions: Draw the structure of the product...

Question 13

Instructions: Draw the structure of the aldol self-condensation product of each compound for the following question(s). If a compound does not undergo aldol self-condensation, explain why it does not.
Draw and explain:

Accepted Answer

The answer of Instructions: Draw the structure of the aldol...

Question 14

Instructions: Consider the reaction below to answer the following question(s).
 Refer to instructions. Which carbonyl compound functions as the electrophile in this reaction?

Accepted Answer

The answer of Instructions: Consider the reaction below to answer...

Question 15

When treated with base and heat, the following diketone undergoes an intramolecular aldol reaction followed by dehydration to produce cis-jasmone, a perfume component. Draw the structure of the product.

Accepted Answer

The answer of When treated with base and heat, the...

Question 16

Identify products a and b.

Accepted Answer

The answer of Identify products a and b.

...

Question 17

Instructions: Consider the structures below to answer the following question(s).
 Refer to instructions. Rank the molecules above in order of increasing acidity (least acidic to most acidic).

Accepted Answer

The answer of Instructions: Consider the structures below to answer...

Question 18

Instructions: Draw the structure of the product you would expect to obtain by Claisen condensation of the esters shown in the question(s) below. If an ester does not undergo Claisen condensation, explain why it does not.
Draw and explain:

Accepted Answer

The answer of Instructions: Draw the structure of the product...

Question 19

Instructions: Consider the reaction below to answer the following question(s). Refer to instructions. Write the complete stepwise mechanism for the reaction above. Show all intermediate structures and all electron flow with arrows.

Accepted Answer

The answer of Instructions: Consider the reaction below to answer...

Question 20

Instructions: Give the major organic product(s) of each reaction or sequences of reactions for the following question(s). Show all relevant stereochemistry.
Give major product(s):

Accepted Answer

The answer of Instructions: Give the major organic product(s) of...

Quiz 11: Carbonyl Alpha-Substitution Reactions and Condensation Reactions

Instructions: Draw the structure of the aldol self-condensation product of each compound for the following question(s). If a compound does not undergo aldol self-condensation, explain why it does not. Draw and explain:

Instructions: Consider the reaction below to answer the following question(s). Refer to instructions. Draw the structure of the enolate ion that is generated during the course of this reaction.

Instructions: Consider the structures below to answer the following question(s). Refer to instructions. Underline the acidic hydrogen atoms in each of the molecules.

Which of the following does not possess an enol form? Explain your choice.

Instructions: Consider the reaction below to answer the following question(s) . Refer to instructions. This reaction is an example of:

Instructions: Draw the structure of the aldol self-condensation product of each compound for the following question(s). If a compound does not undergo aldol self-condensation, explain why it does not. Draw and explain:

Predict the major aldol product of the following reaction.

Instructions: Consider the reaction below to answer the following question(s) . Refer to instructions. The product of this reaction is:

Rank the following hydrogens in terms of decreasing acidity (most acidic > least acidic):

Instructions: Draw the structure of the product you would expect to obtain by Claisen condensation of the esters shown in the question(s) below. If an ester does not undergo Claisen condensation, explain why it does not. Draw and explain:

Instructions: Draw the structure of the aldol self-condensation product of each compound for the following question(s). If a compound does not undergo aldol self-condensation, explain why it does not. Draw and explain:

Instructions: Consider the reaction below to answer the following question(s). Refer to instructions. Which carbonyl compound functions as the electrophile in this reaction?

When treated with base and heat, the following diketone undergoes an intramolecular aldol reaction followed by dehydration to produce cis-jasmone, a perfume component. Draw the structure of the product.

Identify products a and b.

Instructions: Consider the structures below to answer the following question(s) . Refer to instructions. Rank the molecules above in order of increasing acidity (least acidic to most acidic) .

Instructions: Draw the structure of the product you would expect to obtain by Claisen condensation of the esters shown in the question(s) below. If an ester does not undergo Claisen condensation, explain why it does not. Draw and explain:

Instructions: Consider the reaction below to answer the following question(s). Refer to instructions. Write the complete stepwise mechanism for the reaction above. Show all intermediate structures and all electron flow with arrows.

Instructions: Give the major organic product(s) of each reaction or sequences of reactions for the following question(s). Show all relevant stereochemistry. Give major product(s):