A particular gene has a mutation in its NFR that causes it to bind abnormally tightly to histones. What effect would you expect this mutation has on the expression of this gene?
A) The expression of the gene would be abnormally high.
B) The effect on gene expression is impossible to predict.
C) The gene would encode a different protein instead.
D) The expression of the gene would be abnormally low or absent.
E) The promoter of the gene will be constantly available to transcription factors and RNA polymerase.

Question

Quizplus · Accepted Answer

When the NFR binds abnormally tightly to histones, it creates a more compact chromatin structure which may prevent access of transcription factors and RNA polymerase to the gene. This ultimately leads to a decrease or complete cessation of gene expression.

A Particular Gene Has a Mutation in Its NFR That