In Burkitt lymphoma, there is increased expression of the MYC gene.Which of the following BEST explains this situation?
A) A chromosome deletion has removed a tumor-suppressor gene.
B) A chromosome deletion has removed an oncogene.
C) There is a chromosome duplication that involves a segment with an oncogene.
D) A translocation has brought the MYC gene next to a different regulatory region.
E) The MYC gene has been amplified.
Correct Answer:
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