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CO Binds More Strongly to the Heme Iron Than O2

Question 32

Multiple Choice

CO binds more strongly to the heme iron than O2 does due to which reason?


A) CO binds to the heme iron perpendicular to the porphyrin ring, allowing maximum electron orbital overlap between CO and Fe2+.
B) CO weighs less than O2, therefore binding to the heme iron more easily.
C) CO binds to the heme iron covalently, while O2 binds via ionic interactions.
D) All of the answers are correct.
E) None of the answers is correct.

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