Which molecule binds MOST strongly to the heme iron? A) N₂ B) O₂ C) CO₂ D) CO E) H₂O

Question

Quizplus · Accepted Answer

CO (carbon monoxide) binds most strongly to heme iron. This is because CO is a very small molecule with a strong, polar bond, which allows it to fit tightly into the heme pocket and form a stable complex with the iron ion. This affinity for heme iron is the reason why CO is so toxic to humans, as it can displace oxygen from hemoglobin in the blood and cause carbon monoxide poisoning.

Which Molecule Binds MOST Strongly to the Heme Iron