Which Statement Is FALSE

Which statement is FALSE?

A) In vitro, the strand-exchange reaction can include formation of a Holliday intermediate.
B) In vitro, the strand-exchange reaction is accompanied by ATP hydrolysis.
C) In vitro, the strand-exchange reaction may involve transient formation of a three- or four-stranded DNA complex.
D) In vitro, the strand-exchange reaction needs RecA protein.
E) In vitro, the strand-exchange reaction requires DNA polymerase.