Reaction steps that are far from equilibrium are good control points in metabolic pathways because:
A) the net flux through those steps is easily reversed.
B) the rate differences between the forward and reverse steps are often small.
C) these reactions occur most frequently in the cell.
D) these reactions are highly endergonic.
E) these reactions are highly exergonic.

Question

Quizplus · Accepted Answer

Reactions that are far from equilibrium, meaning they have a large negative Gibbs free energy change (highly exergonic), are often used as control points in metabolic pathways. This is because they are essentially irreversible under cellular conditions, allowing the cell to regulate the flow of metabolites through the pathway efficiently.

Reaction Steps That Are Far from Equilibrium Are Good Control