A patient has a platelet count of 1200 *10⁹/L. Many platelets are giant and have abnormal shapes. A mild anemia is present. The bone marrow has increased megakaryocytes in clusters; iron stores are present. Which of the following is most likely?

Question

Quizplus · Accepted Answer

The platelet count is significantly elevated and the bone marrow shows increased megakaryocytes in clusters, which is consistent with essential thrombocythemia. The presence of giant and abnormal-shaped platelets and mild anemia also supports this diagnosis. Chronic myelogenous leukemia typically presents with increased white blood cell count and the presence of the Philadelphia chromosome. Thrombocytosis secondary to blood loss would not cause such a significant elevation in platelet count, and polycythemia vera would present with increased red blood cell count and hematocrit.

A Patient Has a Platelet Count of 1200 *109/L

A Patient Has a Platelet Count of 1200 *10⁹/L