Although found in most chronic myeloproliferative disorders, increased fibrosis detected by the silver techniques and trichrome stain is the key feature of:

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Increased fibrosis detected by silver techniques and trichrome stain is the key feature of primary myelofibrosis, also known as idiopathic myelofibrosis. The other chronic myeloproliferative disorders may have some degree of fibrosis, but it is not the primary feature. In secondary polycythemia, there is an increase in red blood cell production due to conditions such as hypoxia or EPO-producing tumors. Chronic myelogenous leukemia is characterized by the Philadelphia chromosome and increased granulocytes. Essential thrombocythemia is characterized by increased platelets.

Although Found in Most Chronic Myeloproliferative Disorders, Increased Fibrosis Detected