What is the most common enzyme deficiency of the glycolytic pathway?

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Pyruvate kinase (PK) is the most common enzyme deficiency of the glycolytic pathway. PK deficiency leads to hemolytic anemia due to decreased production of ATP in red blood cells, leading to their premature destruction. Symptoms include fatigue, jaundice, and enlargement of the spleen. Aldolase deficiency is also a rare genetic disorder that affects the glycolytic pathway. Enolase and lactic dehydrogenase deficiencies are not known to be common enzyme deficiencies of this pathway.

What Is the Most Common Enzyme Deficiency of the Glycolytic