What is the best test to confirm the diagnosis of PK?

Question

Quizplus · Accepted Answer

The most reliable test for confirming the diagnosis of pyruvate kinase (PK) deficiency is a PK enzyme assay, which measures the activity of PK in red blood cells. A reduced activity of PK confirms the diagnosis of PK deficiency. Reticulocyte count, haptoglobin test, and urine hemosiderin test may also be used to support the diagnosis, but they are not as specific or sensitive as the PK enzyme assay.

What Is the Best Test to Confirm the Diagnosis of PK