The genome of Streptomyces coelicolor has a high CG content; about 72% of base pairs are GC. Compared with a sequence with 50% G and C, how would the high GC content of S. coelicolor affect the number of fragments obtained by digestion of its DNA with the restriction enzyme DraI (restriction site 5'-TTTAAA-3' )? A)more than would be expected from a random sequence B)less than would be expected from a random sequence C)approximately the same number that would be expected from a random sequence D)It is not possible to determine from the information provided.

Question

Quizplus · Accepted Answer

The high GC content of *Streptomyces coelicolor* means that sequences rich in AT, such as the DraI recognition site (TTTAAA), would be less common, resulting in fewer restriction sites and thus fewer fragments compared to a sequence with 50% GC content.

The Genome of Streptomyces Coelicolor has a High CG Content;